1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
|
prelude: |
bm_so_fasta = <<'EOS'
# The Computer Language Shootout
# http://shootout.alioth.debian.org/
# Contributed by Sokolov Yura
$last = 42.0
def gen_random(max, im=139968, ia=3877, ic=29573)
(max * ($last = ($last * ia + ic) % im)) / im
end
alu =
"GGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGG"+
"GAGGCCGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCGAGA"+
"CCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAAT"+
"ACAAAAATTAGCCGGGCGTGGTGGCGCGCGCCTGTAATCCCA"+
"GCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGG"+
"AGGCGGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCC"+
"AGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAA"
iub = [
["a", 0.27],
["c", 0.12],
["g", 0.12],
["t", 0.27],
["B", 0.02],
["D", 0.02],
["H", 0.02],
["K", 0.02],
["M", 0.02],
["N", 0.02],
["R", 0.02],
["S", 0.02],
["V", 0.02],
["W", 0.02],
["Y", 0.02],
]
homosapiens = [
["a", 0.3029549426680],
["c", 0.1979883004921],
["g", 0.1975473066391],
["t", 0.3015094502008],
]
def make_repeat_fasta(id, desc, src, n)
puts ">#{id} #{desc}"
v = nil
width = 60
l = src.length
s = src * ((n / l) + 1)
s.slice!(n, l)
puts(s.scan(/.{1,#{width}}/).join("\n"))
end
def make_random_fasta(id, desc, table, n)
puts ">#{id} #{desc}"
rand, v = nil,nil
width = 60
chunk = 1 * width
prob = 0.0
table.each{|v| v[1]= (prob += v[1])}
for i in 1..(n/width)
puts((1..width).collect{
rand = gen_random(1.0)
table.find{|v| v[1]>rand}[0]
}.join)
end
if n%width != 0
puts((1..(n%width)).collect{
rand = gen_random(1.0)
table.find{|v| v[1]>rand}[0]
}.join)
end
end
n = (ARGV[0] or 250_000).to_i
make_repeat_fasta('ONE', 'Homo sapiens alu', alu, n*2)
make_random_fasta('TWO', 'IUB ambiguity codes', iub, n*3)
make_random_fasta('THREE', 'Homo sapiens frequency', homosapiens, n*5)
EOS
benchmark:
- name: so_k_nucleotide
prelude: |
script = File.join(File.dirname($0), 'bm_so_fasta.rb')
File.write(script, bm_so_fasta)
def prepare_fasta_output n
filebase = File.join(File.dirname($0), 'fasta.output')
script = File.join(File.dirname($0), 'bm_so_fasta.rb')
file = "#{filebase}.#{n}"
unless FileTest.exist?(file)
STDERR.puts "preparing #{file}"
open(file, 'w'){|f|
ARGV[0] = n
$stdout = f
load script
$stdout = STDOUT
}
end
end
prepare_fasta_output(100_000)
script: |
# The Computer Language Shootout
# http://shootout.alioth.debian.org
#
# contributed by jose fco. gonzalez
# modified by Sokolov Yura
seq = String.new
def frecuency( seq,length )
n, table = seq.length - length + 1, Hash.new(0)
f, i = nil, nil
(0 ... length).each do |f|
(f ... n).step(length) do |i|
table[seq[i,length]] += 1
end
end
[n,table]
end
def sort_by_freq( seq,length )
n,table = frecuency( seq,length )
a, b, v = nil, nil, nil
table.sort{|a,b| b[1] <=> a[1]}.each do |v|
puts "%s %.3f" % [v[0].upcase,((v[1]*100).to_f/n)]
end
puts
end
def find_seq( seq,s )
n,table = frecuency( seq,s.length )
puts "#{table[s].to_s}\t#{s.upcase}"
end
input = open(File.join(File.dirname($0), 'fasta.output.100000'), 'rb')
line = input.gets while line !~ /^>THREE/
line = input.gets
while (line !~ /^>/) & line do
seq << line.chomp
line = input.gets
end
[1,2].each {|i| sort_by_freq( seq,i ) }
%w(ggt ggta ggtatt ggtattttaatt ggtattttaatttatagt).each{|s| find_seq( seq,s) }
loop_count: 1
|